fragments are within the intracellular fluid and capable of entering and affecting an undamaged cell

fragments are within the intracellular fluid and capable of entering and affecting an undamaged cell. Such terminated DNA fragments are called ZIPOIDS. Since DNA is the basis of inheritance and life transmission to cells which it originates, the entrance of a Zipoid into a cell is in fact an additional and spurious inheritance factor.

The penetration into a cell of a non-normal short chain of DNA attached to metal ion terminator (a Zipoid) can result in-

1. attachment of the penetrated DNA fragment to the normal DNA, and when thus formed DNA duplicates to make a new cell, the new DNA duplicates to make a new cell with altered DNA. The new DNA continues throughout the reproducing cell line. The new line of cells do not function like the original cell line.

1a. or the penetrated DNA fragment can remain inside the cell as a spurious individual DNA area. When the normal DNA duplicates itself to make a new cell, the separate penetrated DNA fragment also duplicates. In the new cell the normal DNA functions to produce messengers and the messengers produce proteins: the spurious DNA also functions to produce spurious Messengers and the messengers produce spurious proteins. The Zipoid does not destroy the cell at once on entering.

2. DNA fragments of intermediate length, in the intracellular fluid carry numerous programs and signal areas. When terminated with metal ions, they have the ability to penetrate prime cells and reproduce themselves as and with the normal reproduction of DNA FROM CELL TO CELL.

Such a spurious DNA continuing in the cells from generation to

generation, has the effect of increasing, diminishing or otherwise altering the instructions to other functional parts of the cell.

3. a long chain of DNA fragment moving by turbulence in an extracellular fluid carries a large variety of programs that remain capable of activation. These programs include-

programs to initiate cell division, programs to produce DNA to produce proteins enzymes and chemicals. Such a DNA fragment, metal ion terminated and in the intracellular fluid, functions to produce a Messenger RNA on itself and the Messenger RNA functions to produce a protein chain attached to the Messenger DNA and in turn attached to the DNA fragment, resulting in a new assembly of capabilities, still floating in the fluid. The assembly is protected by a protein envelope (which it can lose or regenerate) and is capable, due to metal ion termination, of entering a cell through the cell wall. The termination also carries the key to cause the normal cellular DNA to reproduce a chain like the entering chain. This reproduction results in a new DNA chain duplicating the penetrating fragment while the entering fragment remains intact, but destroying the essential normal DNA of the cell, and therefore the structural integrity of the cell. The two fragments float free in the fluid. Both proceed as a starting long chain fragment and proceed to destructively reproduce themselves. Such a phosphogenetic chain with these acquired capabilities is called a VIRUS. The Viruses are a variety similar in detail but different in composition due to the fact that various long Phosphogenetic fragments are taken from different sections of the prime DNA strings.

VIRUS and VACCINE Similarities

Vaccine is a defense mechanism against a foreign cellular organism and its protein parts. In preparing a vaccine, a culture of the offensive organism is killed and then the dead culture is injected into the fluids of the host. The host makes antibodies (materials which will precipitate specific proteins of the offensive organism). Precipitation and therefore neutralization of the proteins of the offensive invader, occurs on contact with the antibody. The precipitants are planned in the host cell by DNA in the Nub area of cells and made and released by the descendant-service cells. The precipiting materials (sometimes called ANTIBODIES) are made and used in the service cells polymorphonuclear or excreted by the monocyte white cells. Therefore the antibody is a variant of the digestive enzyme found in the polymorph or monocyte white cell. Thus a new, or many new, proteins specific for the invader, are added to the genetic system. The Vaccine is accordingly an antibody-protein (terminated). Essentially, antibodies are a characteristic of the polycellular organisms.

The virus is a fragment of a reproducing part of a RNA (Pointer) chain. (Containing when in the fluid, an attached protein chain and a terminator). After penetration into the cell, and when in the cell it uses the pieces of a host DNA to duplicate itself.

(The invading strand of DNA is "specific" in that it attacks by seeking those strands which contain configurations most similar to the configuration of its own strand). As the virus enters the cell it (having lost protective protein) is ready to reproduce Phosphogenetic chains, seeking cellular- phosphogenetic chains of origin – and therefore composition – similar to itself and also seeking cellular DNA/RNA ready for, or in process of dividing; that is in rapidly reproducing cells. On multiple reproduction the viral

chains fill up the cell and are apt to become terminated by Interferon proteins. The new viruses then disrupt the cell, pass into the intracellular fluid and continue the reproductive process.

- - - - - - - - - - - -

Comparing the two classes of "selective immunity", protein immunity is "specific" originating from the production of a new protein group. The viral attack leaves certain Phosphogenetic strands untouched "immune" because the proposed string for attack does not have the materials –configuration- the viral strand needs to reproduce. The virus is therefore "specific" by difference.

- - - - - - - - - - - -

There is no protein type immunity for the phosphogenetic string of the virus itself. The protein temporarily attached to the virus does generate antibodies to itself since it is a foreign protein. Like the precipitating antibodies generated from any foreign protein, the precipitating antibody can be used to test in vitro the presence of a foreign protein using the simple test of precipitation on mixing the two.

- - - - - - - - - - - -

Virus infections occur in both polycellular and unicellular organisms. In monocellular organisms protein antibodies are not normally formed. Unicellular organisms defend against other organisms by the excretion of "poisons" which are of wide specific range (penicillin, aureomycin, etc.).

ENZYMES DO NOT PROPAGATE CELL TO CELL.

VIRUSES DO PROPAGATE FROM ONE CELL TO ANOTHER

AND CONTINUE MULTIPLYING IN MANY CELLS SEQUENTIALLY

Preparation of a Virus

Since a virus is a fragment of a phosphogenetic chain which discontinued its normal function within a cell and exists in fluid outside the cell and is terminated with a metallic ion and any attachments to the ion, the preparation of and maintenance of a Virus capable of propagating itself by duplicating itself within and destroying, similar to its origin cells, in process of active reproduction in a cell culture, can be artificially done by taking a number of cells and some intracellular fluid away from the mother culture, and in a separate vessel subjecting these cells to mechanical stress resulting in the release of phosphogenetic material from the cells and then providing metal(s) in suitable form for termination with the released DNA/RNA, thus yielding a fluid separate from the mother culture and containing a Virus. The thus contained virus in the now viral fluid, on admixture with the cells of the main mother culture, proceed to propagate Virus by invading cells of the main culture and using the cellular DNA/RNA to produce more virus. The rapidly growing cell cultures of many unicellular organisms and cell culture groups of cells of many polycellular organisms where cells are in rapid conditions of functioning have formed the basis of artificial cell-to-virus systems.

It is therefore possible to select a group of original cells in an extracellular fluid and divide into a number of aliquots, to take a separate aliquot portion of the cellular fluid and convert into a virus containing fluid, to test the virus

containing substance for the presence of virus by combining the virus portion with an aliquot of the original portion and (if virus present) noting that the original cells break up and cease to function while the standard aliquot continues to function normally. Thus a virus can be made and a test made available to evaluate the virus. This is the cell-virus-cell system .

Having established a cell-virus-system and repeated the operation of same many times, the system provides a means of testing the efficiency of antiviral material. The test for an effective antiviral material is to get the cell-virus-cell system working and during the operation of one of the runs add some antiviral material to the virus portion and observe if the virus can propagate in the mother aliquot.

As a result of the above there is available a SUBSTANCE ANTI-VIRUS EFFECT TEST (SAVET TEST)

The steps of which include:

1. a set of original rapidly growing cells in a cell culture is divided into aliquots-

2. one of the separate portion aliquots containing the cells is converted into a virus containing portion by agitating the cells to the break point in the presence of metallic oxides, metallic derivatives and metallic coordinates.

3. testing the thus engendered aliquot material from step 2 by mixing with an aliquot of the original set of cells and observing the break up of the original cells and their changed functionability (using a microscope if needed). A break up is presumptive evidence of virus. But continuing and extending the test by

4. testing the ability of the "synthetic" virus having an original effect to propagate further using the technique of mixing the virus containing material of part 3 above with a new aliquot of the original culture and observing the activity of the propagated virus. The observance of cell destructive activity constitutes confirmation of the presence of the virus.

The SAVE TEST having established a means of making and testing a virus, also provides a means of testing the anti viral activity of any proposed chemical composition as being useful as a POLYMER FOR DESTROYING VIRUS.

The virus destruction test consists of adding some of the "test" polymer for destroying virus to step 3. in a separate test series of a progressing SAVE TEST, and if the polymer for destroying virus is effective, observing that the next aliquot which the virus would destroy is not destroyed. This VIRUS DESTRUCTION TEST provides a means of evaluating a POLYMER FOR DESTROYING VIRUS rapidly and expeditiously.

In any cell, although it excretes enzymes and other chemicals into the fluid surrounding it, and even though it absorbs materials from the surrounding fluid or environment to which it contributes, Phosphogenetic materials do not- by design- normally leave the cell.

The phosphogenetic material found outside the cell results from mechanical fragmentation of the cell. The phosphogenetic material which gets out of the cell, being shorter in chain length than the cellular phosphogenetic chains, either disintegrate or form derivatives by reaction with nearby chemicals or various other cellular debris to form viral phosphogenetic strands.

The essential phosphogenetic strands of the DNA of the virus do not differ from the strands (not the termination) of the cellular DNA except as to positions between the cell exterior and the cell interior. Up to the present, chemicals or polymers intended to cause changes in the phosphogenetic chain in the virus and other undesirable phosphogenetic substances while in the extracellular fluid also are of such configuration as to penetrate the cell and have an action on the phosphogenetic strings, chains, polymers, and therefore genes within the cell.

Thus heretofore used chemicals and polymers which act on phosphogenetic chains are not specific as to the PLACE where the action occurs.

The result is that presently used chemicals and polymer treatments intended to alter or restrict the functioning of the viral RNA in the fluid, also have the undesirable effect of attacking and altering the normal and established functioning which forms part of the genes within the cell resulting in serious malfunctions of the individuals of which the cell is a part.

Anti-virus treatment.

In anti viral treatment of a virus carrying individual, it is therefore necessary to employ phosphogenetic inactivators or modifiers which, while effecting and rendering the virus in the extracellular fluid, will not penetrate the cell and unfavorably alter the gene functioning of the cell itself.

Using herein disclosed materials of configuration such as to inactivate the phosphogenetic functionality of the virus, and such materials not entering the cell, the result is the virus cannot multiply or survive, while the cell and the individual of which it is a pert continues a normal course of life.

It occurred to me that in preparing an antiviral treatment, it is essential to modify or otherwise affect viral-DNA in the fluid, using agents that will not penetrate the cell and thus avoid interference with the normal functioning DNA.

The virus is thus a chain of phosphogenetic material originating from a string of RNA polymer

being similar to a portion of an RNA chain. The virus chain is terminated at one end by a metal ion; at the other end by one of possibly many protein fragments. The virus is formed when a fragment of RNA circulates outside the cell and acquires metal ion and protein fragments while it is in the extracellular fluid.

The formed virus penetrates a suitable cell- with the aid of the protein fragment temporarily attached to it. In the cell, the formed virus loses the protein fragment and attacks the RNA chain by first breaking it using the metal ion terminal as the breaker. Thereafter the Virus (using the metal ion terminal) reassembles step by step ((as detailed in the following under Polymers)) a phosphogenetic string in accordance with the pattern on the Virus.

This produces another new duplicate to the Virus string- the Chip string- which is a duplicate of the formed virus string.

Then both original Virus and Chip Virus leave the now disrupted cell, circulate in the intracellular fluid, proceed to acquire metal ion and protein terminals and proceed to attack other suitable cells. Chemical or cell-debris material in the intracellular fluid may attach or alter the Virus into a changed form resulting in somewhat changed action characteristics. If the alteration enhances the capability of the Virus, the altered Virus on reproduction continues its cell to cell cycle as a new variant of the virus. If the change is not favorable, the changed entity simply does not function and the many original Viruses in the intracellular fluid continue functions.

----------------

Appropriate methods for halting the action of the Virus is one or more of the following actions.

Outside the cell proper and within the extracellular media-

Remove the terminal protein-

Replace the terminal protein-

Replace the terminal ion with an ion that will not cause the starting effect of the virus on the normal cellular chain-

Lyse the viral phosphogenetic chain with a material that will not disturb the cellular chain, and terminate the lysed fragments with a non functional ion-

Block the side saccharide-cyclic-amine groups of the Viral chain thus spoiling ability to duplicate-

Cause the virus to react with parts of a foreign phosphogenetic chain from which it cannot release-

Introduce a chain that will lyse the viral chain-

Block each phosphorus atom in the viral chain with a phosphorus reactor.

-------------------

However any method effective in halting the action of a Virus is primarily dependent on altering the basic functioning structure of the Virus to a condition such that it cannot reproduce.

The Phosphogenetic chain of both the virus and the cellular DNA/RNA chains consist of a Phosphate and a saccharide chain with side groups of cycloamines of which only four are used. These are in the RNA: adenine, cytosine, guanine, uracil. But in DNA thyamine is used in place of uracil. Adenine and Guanine are purines: Cytosine, uracil and Thyamine are pyrimidines.

Each cycloamine is different in size and reactive sites, but the function of reproduction and protein assembly is by space fit, (like the perforations or voids and their distance apart in a punched card used in the punched card computer to determine the impulses sent to the computer and therefore the information transmitted). The phosphogenetic chains operate generally in a protected sheath. The DNA is a delicate chain. The normal and useful cycloamines listed above are easily replaced by cycloamines (and chemicals) other than the four listed. The replacement occurs at the nitrogen, where the cycloamine is attached to the sugar.

When one of the cycloamines is replaced by a chemical of another structure, when functioning

the normal fit-function cannot occur with the result that a portion of the phosphogenetic chain is non functional or of altered function. When a number of foreign replacements occur,

the output products show great variance from the norm.

Materials capable of replacing the purines and pyramadines which are essential in the normal genetic chain are called REPLOFILES. Among the known replofiles are:

dichlorpurine(dcp) (a reported cause of growth variations)

phthalamid(pta) (a cause of growth abnormalities)

imidazole dimethonine(idm) (a reported cause of neoplasms)

azaccytocidene(azc) (a reported cause of malignancy)

azaguine(sgz) (in RNA prevents protein formation)

caprolactam (prevents normal organ formation)

amino acridine hydrochloride monohydrate(aap) (prevents nitrogen metabolism)

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The replacement materials (replofiles) as listed above (and others) are low in molecular weight (less than 500). When one of them is used to stop the action of a virus by reacting with the phosphogenetic chain of the virus, the chain may be altered and rendered non functional as a virus. However the replacement replofile also- due to its small size- also enters the normal cells and causes serious changes in the normal phosphogenetic chains and makes them of non function or of harmful function. This means the listed replofiles, as medical treatments used as limiting the action of a virus, are of little or no value because of dangers they impart to the normal functioning of the cellular genes.

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The carboxy containing REPLOFILES available which contain functional groups capable of attaching to a hydroxyl ended

the output products show great variance from the norm.

Materials capable of replacing the purines and pyramadines which are essential in the normal genetic chain are called REPLOFILES. Among the known replofiles are:

dichlorpurine(dcp) (a reported cause of growth variations)

phthalamid(pta) (a cause of growth abnormalities)

imidazole dimethonine(idm) (a reported cause of neoplasms)

azaccytocidene(azc) (a reported cause of malignancy)

azaguine(sgz) (in RNA prevents protein formation)

caprolactam (prevents normal organ formation)

amino acridine hydrochloride monohydrate(aap) (prevents nitrogen metabolism)

----------------

------------

The carboxy containing REPLOFILES available which contain functional groups capable of attaching to a hydroxyl ended

polymer which polymers have molecular weight in the range of 2500-25000 include:

carboxy pthalamid

1,2 epi dimethyl amid, 4 carboxl, 5methyl benzene

indole 3 acetic acid

2 imidazolidone 4 carboxylic acid

pyridoxil carboxylic acid

dihydropyridine dicarboxylic acid

dimethyl pyrolle carboxylic acid

4 hydroxy 4 carboxy pentamethylene imine (citramid)

urea muconic acid

These are representative of a group of compounds that contain a cycloamid group and capable of replacing normal cycloamines from phosphogenetic chains, but said compounds are capable of being attached to a long chain hydroxyl ended polyester through the carboxyl group. Chemicals falling within this classification are called CARBOXY REPLOFILES.

Pthalamid, like AZG interferes with genetic materials inside the cell as it is small enough to penetrate the cell. Pthalamid also, like AZG, causes stasis of genetic activity in the extracellular fluids serum and lymph. As such, Pthalamid and AZG are not useful as antiviral agents because normal cell genetic material as well as virus genetic material are both effected by the chemical causing stasis of genetic material.

I have discovered if a long chain (hydroxyl terminated polyester) polymer is made, a pthalamid group may be introduced into the polymer using the carboxy function of carboxy-pthalamid, then the polymer group contains pthalamid functions as terminators and side groups in the polymer mole, and when the polymer is large enough in size, then it will not penetrate the cell, then the cell contents including genetic material are protected, but the polymer being miscable in serum and lymph makes available pthalamid groups, and thus interferes with any phosphogenetic material including virus genetic material that may be in the fluids. Then viral stasis occurs, even if the virus is in various stages of mutation. Since the polymer-pthalamid is non cell penetrating, large doses can be safely administered

(even as an ointment).

I have used a polyester polymer as the non-cell penetrating chain and attached to this chain in a permanent fashion the pthalamid function. Thus on contact between the polymer and the virus in the serum, the virus is altered to a non functional condition, but the similar genetic system within the cell is not effected because the polyester polymer is too large to enter the cell, but it floats free in the serum cleaning out the virus chains.

I have found that a polyester of XX to XX repeating units of (XXXXXXX XXXX to XXXXXXXXXX XXXXXXX) is within a range satisfactory to prevent penetration into cells from aqueous and biological media and that the polyester chain is not lysed in the extracellular fluids, and the product of the termination of these polyester chains with XXXXXXX XXXXXXXXXX are not lysed in the biological liquid media.

I have particularly found that a polymer of XX repeating units of <XXXXXXXX XXXXXXX> terminated at both ends using XXXXXXX XXXXXXXXX and containing XX side chains of XXXXXX XXXX is non toxic to cellular growth, but when in contact, in fluid, with the AIDS virus, and alternatively with the Herpes virus, and alternatively with the bacteriophage virus, and alternatively with the mini-vertebrate virus, to effectively and completely cause a halting and cessation of the activity of the virus involved.

I have also found that a polymer of XX repeating units of <XXXXXX XXXXXX> monomer terminated at both ends by a XXXXXX XXXXXXXXX, when in contact in the fluid with the Herpes virus, the AIDS virus, or alternatively the bacteriophage virus or the yeast virus or the mini-vertebrate virus to promptly stop the virus activity, and to be non-toxic to B.Coli culture.

Example 1

Polymer XXXX was prepared as follows;

Starting mat’l mols mol-wt mols x mol wt XXX grm mol wt

XXXXXXXXX XX XX XXXX XXX

XXXXXX XXXX XX XXX XXXX XXXX

XXXXXXXX XXXX X XXX XXX XXX

Total XXXX

Water Loss XX XX XXX

XXXXXXX XXXX XXXX actual yield

Processed the above XX XXXXXXXXX until evolution of water XXXXXXX. Yield XXXX grams of Polymer XXXX

- - - - - - - - - - - - - -

Preperation of termination of Polymer XXXX with XXXXXXXXXXXXXXXXX

XXXX polymer XXXX grams XXXXX gram mols XX XXXXXXXX

XXXXXXX XXXXXXXXX XXXX grams XXXXX gram mols

Processed the above XXXX ingredients at XXXXXXXXX until the mass was clear hot and then until a drop cooled to XXXXXX was clear. The resulting polymer was a clear viscous liquid, designated OCT57.

_______________

An Infra-red scan of the product OCT57 indicated the amid group in the expected place for amid, the carbonyl confirming the presence of esters and absorption in the appropriate positions The toxicity to monocellular life forms was tested by adding the polymer OCT57 in the ratio of 5 grams of polymer to 100 grams of a fresh rapidly growing yeast culture. Comparing culture with OCT57 polymer in it against an identical culture without any OCT57 polymer added, showed no change in the rate of growth or nature of fermentation product resulting. This toxicity test was repeated twice with the same result.

INFRA RED SCAN POLYMER OCT57

CAPILLARY FILM PERKIN ELMER INSTRUMENT 710B

WAVE NUMBER (CM-1) 4(CM-1) RESOLUTION

3500-3490 SHARP PEAK -CNHC-

3460 BROAD ABSORB N IN RING

2970 PEAK DISTR –NH-

2510 SMALL BLIP UNIDENTIFIED

1755 PEAK 1’2’4’ SUBST AROMATIC

1700-1745 BROAD PEAK XXXXXX XXX

1365-1375 BROAD PEAK XXXXXXXX XXXXX XXX

1450-1460 BROAD PEAK CH2 IN CYCLIC FORM

1410 SHARP PEAK CH2 BEND

1240 SHARP PEAK RING FORMATION

1145-1190 BROAD PEAK -CH2- CHAINS

1100 SHARP PEAK -(C=O)-C-

720 SHARP PEAK ADJACENT HYDROGENS ON

AROMATIC

CONFIRMS XXXXXXXX XXXXXX XXXX XXXXXXXXX WITH AROMATIC XXXX XXXXXXXXXXX AND XXXXXXXXX XXXX XXXXX.

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Woodruff -I- -II- -IV- HOMEH.C. WOODRUFF 1988 - Pocket Theory Publishing 2004 - MALLEUS.NET